Interleukin-27 Gene Delivery for Modifying Malignant Interactions Between Prostate Tumor and Bone
نویسندگان
چکیده
منابع مشابه
Investigation of the relationship between prostate specific antigen doubling time and the severity of a malignant tumor of the prostate
Background: Prostate cancer has been reported as a worldwide important kind of cancer and the second most common cause of cancer-related mortality among men. Prostate-specific antigen (PSA) serum level is one of the most important markers of prostate cancer diagnosis. While PSA level helps predict the risk of prostate cancer development, researchers still looking for ways to increase the accura...
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primary bone tumors are the sixth most common neoplasm occurring in children and constitute approximately 6% of all childhood malignancies with a peak incidence in 15- to 19-year- old individuals. these lesions are the third most common tumors in adolescents and young adults (exceeded only by leukemia and lymphoma) common complaints are intermittent to constant mild to severe pain, constitution...
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There are emerging data on novel tumor markers such as matrix metalloproteinase-2 (MMP-2 or gelatinase-A), which play a key role in tissue invasion and metastasis. We designed an investigation to assess the usefulness of MMP-2 activity as compared to prostate specific antigen (PSA) in cancer staging process. We have analyzed the circulating form of MMP-2 in serum samples of patients suffering f...
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Clohisy, DR; +Ramnaraine, ML; Lynch, CM; Pan, W; Donahue, JM +Department of Orthopedic Surgery, University of Minnesota, Minneapolis, MN [email protected] INTRODUCTON: One of the most significant advances in understanding the pathophysiology of bone metastases has been the discovery that intense osteoclastogenesis occurs at sites of tumor (1), a feature common to both primary bone sarcomas and m...
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ژورنال
عنوان ژورنال: Human Gene Therapy
سال: 2013
ISSN: 1043-0342,1557-7422
DOI: 10.1089/hum.2013.091